VIIBRYD® (vilazodone HCI) is a prescription medicine indicated for the treatment of major depressive disorder (MDD) in adults.
VIIBRYD and other antidepressants may increase suicidal thoughts or actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. VIIBRYD is not for use in children.
Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions. Some people, including those with (or a family history of) depression, bipolar illness, or a history of suicidal thoughts or actions may have a higher risk of suicidal thoughts or actions. Pay close attention to and call your healthcare provider right away to report any new or sudden changes in mood, behavior, thoughts or feelings.
Call your healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:
Do not take VIIBRYD if you take a monoamine oxidase inhibitor (MAOI), have taken or will take an MAOI within 14 days of taking VIIBRYD, or are being treated with the antibiotic linezolid or intravenous methylene blue.
Serotonin Syndrome: A potentially life-threatening problem that can happen when VIIBRYD is taken with certain other medicines. Stop taking VIIBRYD and call your healthcare provider or go to the nearest emergency room right away if you have any of the following: agitation; hallucinations; confusion, coma; fast heart beat; blood pressure changes; dizziness; sweating; flushing; high body temperature; tremors, stiff muscles, or muscle twitching; loss of coordination; seizures; nausea, vomiting or diarrhea
Increased chance of bleeding: Taking VIIBRYD with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), warfarin, or blood thinners may add to this risk. Tell your healthcare provider right away about unusual bleeding or bruising
Manic episodes: Symptoms may include greatly increased energy; severe trouble sleeping; racing thoughts; reckless behavior; unusually grand ideas; excessive happiness or irritability; talking more or faster than usual
Discontinuation symptoms: Do not suddenly stop VIIBRYD without first talking to your healthcare provider. Stopping VIIBRYD suddenly may cause serious side effects including: nausea; sweating; changes in mood; headache; irritability and agitation; tiredness; dizziness; problems sleeping; electric shock sensation; hypomania; anxiety; ringing in your ears; confusion; seizures
Seizures or convulsions
Glaucoma (angle-closure glaucoma): VIIBRYD may cause an eye problem called angle-closure glaucoma. Call your healthcare provider if you have changes in your vision or eye pain
Low salt (sodium) levels in the blood: May be serious and may cause death. Elderly people may be at greater risk for this. Symptoms may include headache; difficulty concentrating; memory changes; confusion; weakness and unsteadiness which can lead to falls
In severe or more sudden cases, symptoms include hallucinations; fainting; seizures; coma; respiratory arrest; death.
Call your doctor for medical advice about side effects.